АНО ЦСРЗ «Медицинский Партнер» приглашает вас на 4-й международный симпозиум SPIN 2019, который состоится в Парме, Италия, 7-8 июня 2019 года. В этот научный форум включен 34-й Международный семинар по замене поверхностно-активных веществ, который был основан профессором Бенгтом Робертсоном, Стокгольм и группа специализированных европейских неонатологов и ученых, заинтересованных в фундаментальных и клинических исследованиях сурфактантов. Эта группа внесла значительный вклад в огромный прогресс в лечении респираторных заболеваний новорожденных за последние несколько десятилетий и недавно решила расширить сферу охвата этого симпозиума, включив в него все аспекты медицины новорожденных.
В ходе симпозиума последние результаты исследований сурфактантов, новые методы введения сурфактантов и спектр соответствующих клинических тем будут критически обсуждены и представлены высокоуважаемыми экспертами.
Этот симпозиум характеризуется своей дружеской атмосферой, которая позволит стимулировать и плодотворно обмениваться идеями. Мы очень надеемся, что вы сможете присоединиться на конференции SPIN 2019.
08:30
WELCOME + INTRODUCTION
Tore Curstedt, Stockholm, Sweden; Henry L. Halliday, Belfast, UK
08:45
11th BENGT ROBERTSON MEMORIAL LECTURE
Bronchopulmonary dysplasia: 50 years after the original description
Eduardo Bancalari, Miami, USA
09:30
LESSONS FROM THE PAST
Henry L. Halliday, Belfast, UK
10:00
Discussion
10:15
COFFEE BREAK
Chairpersons: Haresh Kirpalani, Halifax, Canada; Charles C. Roehr, Oxford, UK
10:45
THE CHANGING LANDSCAPE IN SUPPORTING PRETERM INFANTS AT BIRTH
Arjan B. te Pas, Leiden, The Netherlands
11:15
THE GOLDEN MINUTE IN THE DELIVERY ROOM: WHAT IS NEEDED?
Ola D. Saugstad, Oslo, Norway
11:45
Discussion
12:00
FREE COMMUNICATIONS
12:00
In vivo tracing of pulmonary exogenous surfactant by 13C natural abundance approach
S. Giambelluca1, F. Ricci2, M. Simonato1, L. Vedovelli1, A. Correani3, C. Casiraghi2, M. Storti2, A. Mersanne2, P. Cogo4, F. Salomone2, V. P. Carnielli3 (1Padova; 2Parma; 3Ancona; 4Udine, Italy)
12:15
Drug induced regulated hypothermia using VH-N439, a neurotensin analogue conjugated to a brain penetrant peptide: A study in newborn piglets
G. Jacquot1, R. Solberg2, M. Masse1, J. Barlinn2, B. Dotinga2, M. Melheim2, P. Lecorche1, J. Temsamani1, M. Khrestchatisky1, O.D. Saugstad2 (1Marseille,
France; 2Oslo, Norway)
12:30
LUNCH BREAK
Chairpersons: Eren Özek, Istanbul, Turkey; Henrik Verder, Holbæk, Denmark
13:30
POSTER PRESENTATIONS
Is nasal septum-tragus length measurement safer in determining endotracheal intubation depth in neonates?
O. Uygur1, M.Y. Oncel1, G. Kadioglu Simsek2, N. Okur3, K. Celik3, O. Bozkurt4 et al (1Izmir; 2Ankara; 3Diyarbakır; 4Şanlıurfa, Turkey)
Short term outcome of late preterm infants compared to term infants – a case-control study
C. Zgârcea, M.L. Ognean, O. Boantă, C. Vlad, A. Ștefan, S. Bunescu, R. Chicea (Sibiu, Romania)
Therapeutic hypothermia: Brazilian experience
R.S. Procianoy, A.L.Corso, B.O. Shoenardie, G.P. de Oliveira, R.C. Silveira (Porto Alegre, Brazil)
Random forest machine learning based prediction of late-onset sepsis and necrotising enterocolitis in preterm infants by using pulse oximetry time series data
N. Aladağ Çiftdemir, I.Güzey, B.Acunaş, Ö.Uçar (Edirne, Turkey)
Conservative versus medical management: Turkish national registry on treatment option and its timing in patent ductus arteriosus (INTERPDA trial)
E.Okulu1, O. Erdeve1, Z. Arslan1, D.U. Usik1, H. Kaya2,I.K. Gocke2 et al (1 Ankara; 2 Malatya,Turkey)
Transcriptome profiling of lung development and hyperoxia-induced lung-injury in a preterm rabbit model of bronchopulmonary dysplasia
M.Storti1, B. Montanini1, F. Ricci1, C. Casiraghi1, A. Mersanne1, M. Lucattelli2 et al. (1Parma, 2Siena, Italy)
TGFβ regulates the establishment of pulmonary alveolar stem cell niche
P. Minoo, R. Ramanathan (Los Angeles, USA)
Chairpersons: Dominique Haumont, Brussels, Belgium; Umberto Simeoni, Lausanne, Switzerland
14:30
EVIDENCE BASED SUPPORT OF THE RED CELL MASS IN EXTREMELY PRETERM INFANTS
Haresh Kirpalani, Hamilton, Canada
15:00
WORK IN PROGRESS – FREE COMMUNICATIONS
Optimizing neonatal care at the Saint Camille Hospital, Ouagadougou (Hosco), Burkina Faso – impact of the neonatal essential survival technology (NEST) continuous quality improvement (QI) program
P. Ouedraogo1, V. Bissyande1, P.E. Villani2, L. Tubaldi3, J. Bua4, F. Uxa 5, C. Dell’Anna6, M.A. Thomson7, C. Plicco8, M.P. Chiesi 8 (1Ouagadougou,
Burkina Faso; 2Brescia; 3Macerata; 4Trieste, Italy; 6Cary, USA; 7Uxbridge, UK; 8Parma, Italy)
15:30
Maternal paracetamol preceeding preterm delivery associated with umbilical cord PH
A. Laitala, T. Saarela, O. Aikio, M. Hallman (Oulu, Finland)
15:45
COFFEE BREAK
16:15
IMMUNO-NUTRITION FOR PRETERM INFANTS
William Mc Guire, York, UK
16:45
PRETERM NUTRITION: STILL CONTROVERSIAL AFTER ALL THESE YEARS
Neena Modi, London, UK
17:15
Discussion
17:45
Adjourn
Chairpersons: Mikko Hallman, Oulu, Finland; Christian P. Speer, Wuerzburg,Germany
08:30
DEVELOPMENT OF SYNTHETIC SURFACTANT FOR CLINICAL USE
Tore Curstedt, Stockholm, Sweden
09:00
CLINICAL TRIALS WITH SYNTHETIC SURFACTANT
David G. Sweet, Belfast, UK
09:30
NOVEL SURFACTANT ADMINISTRATION TECHNIQUES: WILL THEY CHANGE OUTCOME?
Roger Soll, Burlington, USA
10:00
Discussion
10:30
COFFEE BREAK
11:00
FREE COMMUNICATIONS
Chairpersons: Jan Johansson, Huddinge, Sweden; Richard Plavka, Prague, Czech Republic
11:00
Efficacy and safety of synthetic surfactant (CHF5633) versus porcine surfactant, Poractant Alfa in the treatment of respiratory distress syndrome in preterm infants: A multicenter, double blind randomized clinical trial
R. Ramanathan1, M. Biniwale1, K. Sekar2, N. Hanna3, S. Golombek4, J. Bhatia5, M. Naylor6, L. Fabbri7, D. Santoro7, A. Piccinno7, C. Dammann8 (1Los Angeles; 2Oklahoma; 3Stony Brook; 4Valhalla; 5Augusta; 6Greenville, USA; 7Parma, Italy; 8Boston, USA)
11:15
Synthetic surfactant preparations containing a recombinant SP-B and SP-C analogue are efficient against respiratory distress syndrome in a premature rabbit model
O. Basabe-Burgos1, A. Rising1,2, T. Curstedt3, J. Johansson1 (1Huddinge; 2Uppsala; 3Stockholm, Sweden)
11:30
Dose-dependent improvement of lung function after nebulized poractant alfa administration to lung-lavaged, spontaneously-breathing adult rabbits with respiratory distress
F. Ricci1, C. Catozzi1, X. Murgia2, M. Simonato3, B. Rosa1,4, G. Pieraccini4, G. Moneti4, L. Lorenzini1, F. Bianco1, S. Catinella1, G. Villetti1, M. Civelli1, B. Pioselli1, P. Cogo3, V. Carnielli5,C. Dani4, F. Salomone1 (1Parma, Italy; 2Saarbrücken, Germany; 3Udine; 4Florence; 5Ancona, Italy)
11:45
Synthetic surfactant with SP-B and SP-C analogues (CHF5633) improves lung function and attenuates inflammation in an adult rabbit model of acute respiratory distress syndrome
P. Mikolka1,2, T. Curstedt3, R. Feinstein4, A. Larsson4, A. Rising1,4, J. Johansson1 (1Huddinge, Sweden; 2Martin, Slovakia; 3Stockholm; 4Uppsala, Sweden)
12:00
SPECIAL LECTURE
THE VOCALIST IN THE CRIB: DECODING NEONATES’ CRYING
Kathleen Wermke, Wuerzburg, Germany
12:30
LUNCH BREAK
13:30
POSTER PRESENTATIONS
Chairpersons: Corrado Moretti, Rome, Italy; Kris Sekar, Oklahoma City, USA
Lung deposition of nebulized poractant alfa in spontaneously-breathing newborn piglets: Comparison of CPAP versus pressure support ventilation via nasal prongs
A. Nord1, R. Linner1, F. Salomone2, F. Bianco2, F. Ricci 2, X. Murgia3 et al. (1Lund, Sweden; 2Parma, Italy; 3Saarbrücken Germany)
Is lung ultrasound more valuable than X-ray in evaluating the need of surfactant in preterm neonates?
G. Kayki, S. Yigit, H.T. Celik, M. Yurdakok (Ankara, Turkey)
Lung ultrasound in diagnosis and follow-up of neonatal pneumonia
A. Zenciroğlu, A. Öktem, S. Aydoğan, Ç. Üner, D. Dilli, N. Okumuş (Ankara, Turkey)
Characterization of in vitro performance of the customized eFlow neos nebulizer system with poractant alfa under simulated respiratory distress tidal breathing through a realistic neonatal upper airway replica
M. Nutini1, S. Minocchieri2, A. Bucholski3, M. Schlun3, U. Hetzer3, S. Bonelli1 et al. (1Parma, Italy; 2Winterthur, Switzerland; 3Starnberg, Germany)
Nebulized poractant alfa reduces the risk of respiratory failure at 72 hours in spontaneously-breathing surfactant- deficient newborn piglets
C. Rey-Santano1, V. Mielgo1, M.A. Gomez1, F. Salomone2, F. Bianco2, B. Loureiro3 (1,3Barakaldo, Bizkaia, Spain; 2Parma, Italy)
Surfactant administration by the LISA method: 5 years of experience at the Neonatal Resuscitation Centre of the Tivoli University Hospital in Belgium
J. Van Poucke, G. Malfilâtre, J. De Buyst, E. Strebelle, M. Janssens, C. Djeunang et al. (La Louvière, Belgium)
Chairpersons: Sture Andersson, Helsinki, Finland; Roger Soll, Burlington, USA
14:30
LUNG GROWTH IN PRETERM INFANTS
Virgilio Carnielli, Ancona, Italy
15:00
NECROTIZING ENTEROCOLITIS, GUT MICROBIOTA AND BRAIN DEVELOPMENT: ROLE OF GUT-BRAIN AXIS
Boris W. Kramer, Maastricht, The Netherlands
15:30
FREE COMMUNICATIONS
15:30
Hyperoxia injury of saccular stage lung results in mesenchymal expression of WNT5A
J.Sucre, M. Ransom, Z. Anderson, B. Fensterheim, A. Cutrone, C. Jetter, S. Guttentag (Nashville, United States)
15:45
Supplemental oxygen in the first 12 hours of life and less invasive surfactant administration (LISA)
E. Herting1, C. Härtel1, A. Kribs2, W. Göpel1(Lübeck1; Cologne², Germany)
16:00
COFFEE BREAK
Chairpersons: Neena Modi, London, UK; Rangasamy Ramanathan, Los Angeles, USA
16:30
NEW ESPGHAN GUIDELINES FOR TOTAL PARENTERAL NUTRTION IN NEONATES
Jatinder Bhatia, Augusta, USA
17:00
NEW GUIDELINES FOR THE TREATMENT OF NEONATAL RDS
David G. Sweet, Belfast, UK
17:30
Discussion
18:00
CLOSING REMARKS
Scientific Committee